免疫组化技术在病理诊断中的应用

在临床病理诊断中,免疫组织化学(IHC)是一种很重要的技术和手段,从20个世纪70年代开始,免疫组化技术就应用于病理诊断,对于诊断肿瘤、肿瘤分类、判断预后产生了巨大的影响,同时也扩展了人们对于各种疾病及肿瘤形成过程的认识,提高了病理诊断与研究水平。但是,随着免疫组化的广泛应用,发现免疫组化技术存在一些局限性。深入研究免疫组化原理和技术,必须熟悉各种抗体真阳性反应部位,实现实验室间免疫组化标准化,使免疫组化在病理诊断中发挥最大的辅助作用。该文就以上问题作如下综述。

The application of immunohistochemistry in pathological diagnosis

In the diagnosis of clinical pathology,immunohistochemistry(IHC) is a very important technology and tools.The immunohistochemical technique used in the pathological diagnosis started the 1970s,pathologist diagnosis of tumor classification,prognosis had a huge impact,but also extends the understanding of the people for various diseases and tumor formationpathological diagnosis and research..However,with the extensive application of immunohistochemistry,the immunohistochemical technique have some limitations.In-depth study of the principles and techniques of immunohistochemistry,familiar with all kinds of really positive antibody reaction site,and inter-laboratory standardization of immunohistochemistry,play the largest role in support of immunohistochemistry in the pathological diagnosis.This article on the above issues as follows.