Local cerebral blood flow velocity in newborn rats in normocapnia and hypercapnia

The local cerebral blood flow (LCBF) in the caudate nucleus was investigated in experiments on unanesthetized newborn rats by determing the rate of hydrogen saturation of the brain tissue and the cerebral blood volume was studied by plethysmography. LCBF in newborn animals was found to be considerably lower than in adults. Inhalation of CO₂ by newborn, unlike by adult rats, did not cause an increase in LCBF and the cerebral blood volume also remained unchanged.Laboratory of Brain Development, Scientific-Research Institute of Pediatrics, Academy of Medical Sciences of the USSR. (Presented by Academician M. Ya. Studenikin.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 84, No. 8, pp. 139–141, August, 1977.