中文版NoSAS评分在汉族抑郁障碍患者中筛查阻塞性睡眠呼吸暂停综合征的效能分析

目的评估中文版NoSAS评分在汉族抑郁障碍患者中筛查阻塞性睡眠呼吸暂停综合征(OSAS)的有效性,为临床上筛查汉族抑郁障碍患者是否存在OSAS提供参考。方法回顾性分析在无锡市精神卫生中心进行过多导睡眠监测(PSG)并记录有颈围、BMI、打鼾史、年龄及性别等数据的抑郁障碍患者的临床资料。采用ROC分析NoSAS评分对OSAS的诊断价值。NoSAS评分PSG结果用四格表形式计算其灵敏度、特异度、误诊率及漏诊率等数据,并判断其筛查价值。结果以AHI≥5次/h为截点,将258例抑郁障碍患者分为OSAS组和非OSAS组,两组年龄、性别、BMI、颈围、腰围、NoSAS评分、AHI等差异均有统计学意义(P均<0.01)。以AHI≥5次/h为截点时,NoSAS评分预测OSAS的ROC曲线下面积为0.82(P<0.01)。当以AHI≥5次/h、NoSAS评分>8分为截点时,NoSAS灵敏度为59.32%,特异度为83.42%,误诊率为18.09%,漏诊率为40.68%。结论中文版NoSAS评分对于汉族抑郁障碍患者筛查OSAS有较好的预测效能。

Efficacy of Chinese version of NoSAS score in screening obstructive sleep apnea syndrome in Han major depressive disorder patients

Objective To evaluate the efficacy of Chinese version of NoSAS score in screening obstructive sleep apnea syndrome(OSAS)in Han Chinese patients with depressive disorder,so as to provide references for clinical screening of OSAS in patients with depressive disorder of the Han nationality.Methods Retrospective analysis was performed on the clinical data of patients with depression disorder who underwent polysomnography(PSG)monitoring in Wuxi Mental Health Center.The data of neck circumference,BMI,snoring history,age and sex were recorded.The diagnostic value of NoSAS score on OSAS was analyzed by ROC.The sensitivity,specificity,misdiagnosis rate,missed diagnosis rate and other data of NoSAS score were calculated in the form of four tables to judge the screening value.Results With AHI≥5 times/h as the cut-off point,258 patients with depressive disorder were divided into OSAS group and non-OSAS group.There were statistically significant differences in age,gender,BMI,neck circumference,waist circumference,NoSAS score and AHI between the two groups(P<0.01).When AHI≥5 times/h was taken as the cut-off point,the area under the ROC curve of OSAS predicted by NoSAS score was 0.82(P<0.01).When the AHI≥5 times/h and the NoSAS score>8 was the cut-off point,the sensitivity of NoSAS was 59.32%,the specificity was 83.42%,the misdiagnosis rate was 18.09%and the missed diagnosis rate was 40.68%.Conclusion The Chinese version of NoSAS score has a better predictive effect on screening OSAS in Han Chinese patients with depressive disorder.