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人工生物膜对家兔动脉粥样硬化的抑制作用
引用本文:赵蕊,陈明哲,郭静萱,赵一鸣,徐宁生,刘晓勤,赵春玉,孟庆玲,胡大鹏. 人工生物膜对家兔动脉粥样硬化的抑制作用[J]. 北京大学学报(医学版), 1991, 0(1)
作者姓名:赵蕊  陈明哲  郭静萱  赵一鸣  徐宁生  刘晓勤  赵春玉  孟庆玲  胡大鹏
作者单位:北京医科大学第三医院心血管研究室(赵蕊,陈明哲,郭静萱,赵一鸣),北京医科大学第一医院心血管研究室(徐宁生,刘晓勤,赵春玉,孟庆玲),黑龙江牡丹江温春制药厂(胡大鹏)
摘    要:21只日本大耳白兔喂以高脂饲料,灌流脂质体,观察对动脉粥样硬化形成的作用,及其有关检测指标。结果表明,脂质体组主动脉内膜粥样硬化斑块面积、血脂各项指标及血液流变学等均显著改善。说明脂质体对动脉粥样硬化形成有显著抑制作用。

关 键 词:动脉粥样硬化  脂质体  胆固醇

THE INHIBITORY EFFECT OF LIPOSOME ON EXPERIMENTAL ATHEROSCLEROSIS IN RABBITS
Zhao Rui,et al Cardiovascular Rcseach Laboratory,The Third Hospital. THE INHIBITORY EFFECT OF LIPOSOME ON EXPERIMENTAL ATHEROSCLEROSIS IN RABBITS[J]. Journal of Peking University. Health sciences, 1991, 0(1)
Authors:Zhao Rui  et al Cardiovascular Rcseach Laboratory  The Third Hospital
Abstract:We investigated if the Liposome may effect on the formation of atherosclerosis and on theparameters tested. 21 rabbits were fed high-cholesterol diet. The results showed that the size of athe-rosclerotic plaques and TC, HDL-CH, LDL-CH, HDL-PL, TG and blood viscosity were also signifi-cantly decreased. All the above results suggest that the Liposome might inhibit the development ofatherosclerosis in rabbits.
Keywords:Atherosclerosis  Liposome  Cholesterol
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