| 不同产地楮实子提取物体外抗氧化作用及其质量比较 |
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| 引用本文： | 庞素秋,黄宝康,张巧艳,秦路平.不同产地楮实子提取物体外抗氧化作用及其质量比较[J].药学实践杂志,2006,24(3):149-152. |
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| 作者姓名： | 庞素秋 黄宝康 张巧艳 秦路平 |
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| 作者单位： | 1. 第二军医大学药学院生药学教研室,上海,200433;中国人民解放军第180医院药械科,福建,泉州,362000
2. 第二军医大学药学院生药学教研室,上海,200433 |
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| 摘 要： | 目的：对10个不同产地楮实子的乙醇、水提物进行体外抗氧化作用研究，并按中国药典部分质量标准对不同产地的楮实子进行质量比较。方法：采用不同产地的楮实子醇、水提取物对大鼠肝组织匀浆脂质过氧化作用的抑制，评价其体外抗氧化作用，并对不同产地的楮实子的灰分及提取物含量进行比较。结果：不同产地楮实子的抗氧化能力差别较大，其中安徽、山西和广西产的楮实子抗氧化能力最强，灰分含量以山东、浙江和广东三产地的较好。结论：不同产地楮实子的质量有很大差异，其提取物有较明显的体外抗氧化活性，并建议中国药典再版时收栽楮实子提取物含量标准。
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| 关 键 词： | 楮实子 灰分 体外抗氧化 丙二醛 |
| 文章编号： | 1006-0111(2006)03-0149-04 |
| 收稿时间： | 2005-09-22 |
| 修稿时间： | 2005年9月22日 |
Antioxidation effect in vitro and quality comparison of Broussonetia paperifera fruits from different habitats |
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| PANG Su-qiu,HUANG Bao-kang,ZHANG Qiao-yan and QIN Lu-ping.Antioxidation effect in vitro and quality comparison of Broussonetia paperifera fruits from different habitats[J].The Journal of Pharmaceutical Practice,2006,24(3):149-152. |
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| Authors: | PANG Su-qiu HUANG Bao-kang ZHANG Qiao-yan and QIN Lu-ping |
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| Institution: | Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China; Department of Pharmacy, No. 180 Hospital of PLA, Quanzhou 362000, China;Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China |
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| Abstract: | Objective: To study antioxidalion effect of ethanol and aqueous extracts of Broussonetia paperifera fruits from 10 different habitats and assess their qualities by standards of China Pharmacopeia. Methods: MDA production in rats liver homogenate induced by auto-oxidation was measured by MDA kits method and the contents of ashes, elhanol and aqueous extracts were detected. Results: Antioxidation potential of Broussonetia paperifera fruits from Anhui, Shanxi and Cuangxi were significant and contents of ashes were lower from Shandong, Zhejiang and Guangdong than other places. Conclusion: Extracts of Broussonetia paperifera fruits have an-tioxidation effect in vitro, and we suggest that contents of extracts of Broussonetia paperifera fruits be included in next CHP. |
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| Keywords: | Broussonetia paperifera fruits ash content antioxidation effect in vitro malonaldehyde |
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