| 充血性心力衰竭患者血浆内在素与脂质过氧化的关系 |
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| 引用本文： | 刘建国,陶桂华,王风飞,王秉臣,朱永春,李荣华.充血性心力衰竭患者血浆内在素与脂质过氧化的关系[J].中国循环杂志,1995(6). |
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| 作者姓名： | 刘建国 陶桂华 王风飞 王秉臣 朱永春 李荣华 |
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| 作者单位： | 河北医学院附属第二医院 |
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| 摘 要： | 为研究充血性心力衰竭（ＣＨＦ）时血浆内皮素与脂质过氧化的关系，我们观察了４０例ＣＨＦ患者治疗前后及不同心功能状态下血浆内皮素（ＥＴ）和丙二醛（ＭＤＡ）的变化。结果显示：ＣＨＦ患者的血浆ＥＴ及ＭＤＡ均较对照组明显增高（Ｐ＜０．０００１），且其含量均随心功能恶化而增加，治疗后血浆ＥＴ和ＭＤＡ均明显下降，其血浆ＥＴ与ＭＤＡ间呈正相关（Ｐ＜０．０５）。
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| 关 键 词： | 充血性心力衰竭，内皮素，丙二醛 |
THE RELATION BETWEEN PLASMA ENDOTHELIN AND MALONDIALDEHYDE IN CONGESTIVE HEART FAILURE |
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| Liu Jan-Guo, Tao Gui-Hua, Wang Feng-Fei,et al..THE RELATION BETWEEN PLASMA ENDOTHELIN AND MALONDIALDEHYDE IN CONGESTIVE HEART FAILURE[J].Chinese Circulation Journal,1995(6). |
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| Authors: | Liu Jan-Guo Tao Gui-Hua Wang Feng-Fei |
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| Institution: | Liu Jan-Guo, Tao Gui-Hua, Wang Feng-Fei, et al. |
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| Abstract: | In order to study the relation between endothelin (ET) and lipid-peroxidation (LPO) in congestive heart failure, we observed the changes of plasma ET and MDA in 40 cases of CHF with different grades of heart function, before and after treatment. The levels of plasma ET and MDA of CHF patients significantly increased compared with controls (n=15, P<0. 0001)and correlated with the heart function. After treatment plasma ET and MDA decreased markedly. Plasma ET positively correlated with plasma MDA in CHF patients (r-0. 354, p<0. 05). |
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| Keywords: | Congestive heart failure Endothelin Malondialdehyde |
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