| 铜与维生素C协同灭活大肠杆菌噬菌体的机理 |
| |
| 引用本文： | 梁增辉,杨宗芬.铜与维生素C协同灭活大肠杆菌噬菌体的机理[J].中国消毒学杂志,1995,12(1):1-5. |
| |
| 作者姓名： | 梁增辉 杨宗芬 |
| |
| 作者单位： | 军事医学科学院卫生学环境医学研究所 |
| |
| 基金项目： | 国家自然科学基金（38970630） |
| |
| 摘 要： | 用电子自旋共振仪检测维生素Ｃ和硫酸铜混合液的自由基波谱，及其灭活ｆ＿２噬菌体作用。结果表明，维生素Ｃ自由基有较强的灭活噬菌体作用。硫酸铜可提高维生素Ｃ自由基强度，并加速其灭活噬菌体的作用。
|
| 关 键 词： | 灭活病毒机理，协同灭活病毒作用，维生素C，硫酸铜，自由基，f＿2噬菌体 |
MECHANISM OF SYNERGETIC INACTIVATION OF COLIPHAGE f_2 BY COPPER AND VITAMINC |
| |
| Liang Zenghui Yang Zongfen Wangfuyu.MECHANISM OF SYNERGETIC INACTIVATION OF COLIPHAGE f_2 BY COPPER AND VITAMINC[J].Chinese Journal of Disinfection,1995,12(1):1-5. |
| |
| Authors: | Liang Zenghui Yang Zongfen Wangfuyu |
| |
| Abstract: | Vitamin C has
certain inactivating effect on viruses,which is considered as the result offormation of free
radicals in solution. In order to understand the mechanism of synergism ofcopper with vitamin
C in inactivating coliphage f_2, the spectrum of free radicals in mixed so-lution of vitamin C and
CuSO_4 was examined and the relation between the free radicals andinactivation of coliphage
f_2 was observed. The results indicated that no signal of OH·radical and O'_2 radical was
detected in themixed solution of vitamin C (10￣(-3)～10￣(-2)mol / L) and copper sulfate (10￣
(-5)～10￣(-2)mol/L),while the spectrum of double-peak-shaped free radicals of vitamin C was
detected.Thestrength of vitamin C free radical was higher than that in the solution of vitamin C
alone. Thetest for inactivation of phage f_2 indicated that the free radicals of vitamin C had
stronginactivating effect on the phage,The higher the strength of vitamin C free radicals,the
betterthe inactivating efficacy. |
| |
| Keywords: | mechanism of inactivating virus synergism in inactivating virusvitamin C copper sulfate free radical coliphage f_2 |
| 本文献已被 CNKI 维普 等数据库收录！ |
