| 不同采收期何首乌中多元功效物质的动态积累分析 |
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| 引用本文： | 罗益远,刘娟秀,刘训红,兰才武,侯娅,马阳,王胜男,蔡宝昌.不同采收期何首乌中多元功效物质的动态积累分析[J].中国中药杂志,2015,40(13):2565-2570. |
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| 作者姓名： | 罗益远 刘娟秀 刘训红 兰才武 侯娅 马阳 王胜男 蔡宝昌 |
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| 作者单位： | 南京中医药大学, 江苏 南京 210023,南京中医药大学, 江苏 南京 210023,南京中医药大学, 江苏 南京 210023,贵州昌昊中药发展有限公司, 贵州 凯里 556000,南京中医药大学, 江苏 南京 210023,南京中医药大学, 江苏 南京 210023,南京中医药大学, 江苏 南京 210023,南京中医药大学, 江苏 南京 210023 |
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| 基金项目： | 国家科技支撑计划项目(2011BAI13B04);江苏高校优势学科建设工程项目(ysxk-2014);江苏省中药炮制重点实验室开放式课题(zypz007) |
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| 摘 要： | 考察不同采收期何首乌中多元功效物质的动态变化规律,探讨何首乌药材的适宜采收期。采用胶束电动毛细管色谱二极管阵列检测法(MEKC-DAD)测定不同采收期何首乌中二苯乙烯苷、蒽醌类及儿茶素的含量,用主成分分析法对多元功效物质进行综合评价。不同采收期何首乌中多元功效物质的含量呈现动态变化,二苯乙烯苷的含量11月份最高;结合蒽醌的总量11—12月份最高;儿茶素的含量在9月份相对较高;主成分分析综合评价显示,11月份采收的何首乌药材综合评价指数明显高于其他采收期样品。11月份为何首乌药材适宜的采收期,与当地传统采收期基本一致。
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| 关 键 词： | 何首乌 胶束电动毛细管色谱二极管阵列检测法 多元功效物质 动态积累 |
| 收稿时间： | 2015/1/24 0:00:00 |
Dynamic accumulation analysis on bioactive constituents of Polygonum multiflorum in different collection periods |
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| LUO Yi-yuan,LIU Juan-xiu,LIU Xun-hong,LAN Cai-wu,HOU Y,MA Yang,WANG Sheng-nan and CAI Bao-chang.Dynamic accumulation analysis on bioactive constituents of Polygonum multiflorum in different collection periods[J].China Journal of Chinese Materia Medica,2015,40(13):2565-2570. |
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| Authors: | LUO Yi-yuan LIU Juan-xiu LIU Xun-hong LAN Cai-wu HOU Y MA Yang WANG Sheng-nan and CAI Bao-chang |
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| Institution: | Nanjing University of Chinese Medicine, Nangjing 210023, China,Nanjing University of Chinese Medicine, Nangjing 210023, China,Nanjing University of Chinese Medicine, Nangjing 210023, China,Guizhou Chang Hao Chinese Medicine Co., Ltd., Kaili 556000, China,Nanjing University of Chinese Medicine, Nangjing 210023, China,Nanjing University of Chinese Medicine, Nangjing 210023, China,Nanjing University of Chinese Medicine, Nangjing 210023, China and Nanjing University of Chinese Medicine, Nangjing 210023, China |
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| Abstract: | To study the dynamic change law of bioactive constituents from Polygonum multiflorum, and to explore the optimal harvest period of P. multiflorum. Determination of stilbene glucoside, anthraquinones and catechin from P. multiflorum in different harvest times by MEKC-DAD, and principal component analysis (PCA) was used to comprehensive evaluation for bioactive constituents. There are obvious differences among the contents of active ingredients in various collecting periods samples, the content of stilbene glucoside was the highest in November, the total content of combined anthraquinone was the highest in November and December, the content of catechin was the highest in September. The comprehensive evaluation index obtained with principal component analysis showed that the sample collected in November is significantly higher than those with other samples. The optimal harvest period of P. multiflorum is November. |
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| Keywords: | Polygonum multiflorum MEKC-DAD bioactive constituents dynamic change |
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