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Pulsatilla saponin D: The antitumor principle fromPulsatilla koreana
Authors:Yong?Kim,Seong-Cheol?Bang,Ji-Hyun?Lee,Byung-Zun?Ahn  author-information"  >  author-information__contact u-icon-before"  >  mailto:ahnbj@cnu.ac.kr"   title="  ahnbj@cnu.ac.kr"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author
Affiliation:SB Pharmaceutical Co. LTD, 533-2 Bonggok-ri, Banpo-myeon, Gongju-shi 314-923, Chungnam, Korea.
Abstract:By bioassay-guided separation, an already known saponin, Pulsatilla saponin D was isolated from the root of Pulsatilla koreana Nakai as a antitumor component when evaluated by in vivo antitumor activity as well as in vitro cytotoxic activity test. It showed potent inhibition rate of tumor growth (IR, 82%) at the dose of 6.4 mg/kg on the BDF1 mice bearing LLC cells.
Keywords:Pulsatilla saponin D  Antitumor activity
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