Conduction system in systemic lupus erythematosus with atrioventricular block |
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Authors: | Saroja Bharati Domingo J. de la Fuente Ronald J. Kallen Yaser Freij Maurice Lev |
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Affiliation: | 1. From the Congenital Heart Disease Research and Training Center, Hektoen Institute for Medical Research, Chicago, Ill. USA;2. From the LaRabida Children''s Hospital and Research Center, Chicago, Ill. USA;3. From the Departments of Pathology and Pediatrics, Pritzker School of Medicine, University of Chicago, Chicago, Ill. USA;4. From the Department of Pathology, Northwestern University Medical School, Chicago, Ill. USA;5. From the Chicago Medical School, University of Health Sciences, Chicago, Ill. USA;6. From the Loyola University Stritch School of Medicine, Chicago, Ill. USA;7. From the Department of Pathology and Medicine Abraham Lincoln School of Medicine, University of Illinois, Chicago, Ill. USA |
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Abstract: | We describe the clinical course and the postmortem cardiac findings in a 12 year old girl with systemic lupus erythematosus, complete heart block, renal failure and hyperkalemia. The conduction system was examined by serial section. The sinoatrial and atrioventricular nodes were found to be almost completely replaced by granulation tissue; we believe that this finding is related to the systemic lupus. The hyperkalemia is not considered to be the cause of the block, since the block persisted despite the lowering of the blood potassium level and the morphologic findings in this case are not found in hyperkalemia. |
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Keywords: | Address for reprints: Maurice Lev MD 637 S. Wood St. Chicago Ill. 60612. |
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