大肠癌肝转移预测指标 |
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引用本文: | 胡金龙,黄建瑾.大肠癌肝转移预测指标[J].国际肿瘤学杂志,2008,35(8):618-621. |
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作者姓名: | 胡金龙 黄建瑾 |
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作者单位: | 浙江大学附属浙二医院肿瘤内科,杭州,310009 |
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摘 要: | 研究发现在大肠癌肝转移患者中,血管内皮生长因子(VEGF)、p53基因、基质金属蛋白酶(MMP)、骨桥蛋白(OPN)等生物学指标呈现高表达状态,对其检测可以预测大肠癌发生肝转移的可能性,从而对大肠癌患者提早干预,改善预后.
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关 键 词: | 结直肠肿瘤 肝脏 肿瘤转移 肿瘤标记 生物学 |
Parameters for liver metastasis in colorectal cancer |
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Abstract: | Researches find that some biological parameters, such as vascular endothelial growth factor (VEGF), p53 gene, matrix metalloproteinase(MMP) and osteopontin(OPN), are high expressed in the pa-tients of colorectal neoplasm with liver metastases. Detection of these parameters can predict the possibility of liver metastases, then take early intervention and improve the prognosis. |
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Keywords: | Colorectal neoplasms Liver Neoplasm metastasis Tumor markers biological |
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