| 甲磺酸左旋氧氟沙星治疗泌尿道感染临床疗效及安全性 |
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| 引用本文： | 陈永骞,邵强,陈永和,刘志,杨培谦,郭宇文. 甲磺酸左旋氧氟沙星治疗泌尿道感染临床疗效及安全性[J]. 中国新药杂志, 2001, 10(2): 118-120 |
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| 作者姓名： | 陈永骞 邵强 陈永和 刘志 杨培谦 郭宇文 |
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| 作者单位： | 首都医科大学附属北京友谊医院泌尿科, |
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| 摘 要： | 目的：研究甲磺酸左旋氧氟沙星对泌尿道感染的治疗作用及安全性。方案：对30例细菌性泌尿道感染患者静脉滴注甲磺酸左旋氧氟沙星400mg/d,疗程5－7d;对70例泌尿道手术患者术后预防性静脉滴注甲磺酸左旋氧氟沙星400mg/d,疗程5d。结果：治愈率86．7％,有效率93．3％,只有2例（2％）出现了轻度的皮疹;2例（2％）出现肝功能轻度升高反应。结论：甲磺酸左旋氧氟沙星不仅适用于泌尿道感染,而且安全,不良反应少。
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| 关 键 词： | 甲磺酸左旋氧氟沙星 泌尿道感染 治疗 |
| 文章编号： | 1003-3734(2001)02-0118-02 |
The clinical efficacy andsafety of levofloxacin mesylate in treatment of urinary tract infections |
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| Chen Yong-qian,SHAO Qiang,CHEN Yong-he,LIU Zhi,YANG Pei-qian,GUO Yu-wen. The clinical efficacy andsafety of levofloxacin mesylate in treatment of urinary tract infections[J]. Chinese Journal of New Drugs, 2001, 10(2): 118-120 |
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| Authors: | Chen Yong-qian SHAO Qiang CHEN Yong-he LIU Zhi YANG Pei-qian GUO Yu-wen |
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| Abstract: | Objective:To evaluate the efficacy and safety of lev ofloxacin mesylate in treatment of urinary tract infections.Methods:The study was conducted in 30 patients with urinary tract bacterial infection s and 70 patients who are going to receive urinary tract operations.The former p atients were treated with 400mg/d i.v.levofloxacin mesylate for 5～7 d to manag e infections and the latter patients were treated with 400mg/d i.v.levofloxacin mesylate for 5d to prevent infections.Results:A total effective r ate of 93.3% including a cure rate of 86.7% was obtained with 2 cases of mild ra sh(2%) and 2 cases of elevated live r function(2%).Conclusion:Levofloxacin mesylate is an effective an d safe agent for treatment of urinary tract infections with mild side effect. |
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