| 艾可合剂质量标准研究 |
| |
| 引用本文： | 潘旭东,黄燕,林滔,林雄,张敏建.艾可合剂质量标准研究[J].海峡药学,2010,22(6):65-67. |
| |
| 作者姓名： | 潘旭东 黄燕 林滔 林雄 张敏建 |
| |
| 作者单位： | 1. 福建中医学院附属人民医院,福州,350004
2. 福建省皮肤病性病防治院,福州,350009 |
| |
| 摘 要： | 目的建立艾可合剂的质量标准。方法采用TLC法定性鉴别艾可合剂中白芍、赤芍及枳壳;采用HPLC法,以乙腈-水为流动相梯度洗脱,对艾可合剂中柴胡皂苷a进行定量分析。结果定性鉴别分离度好,专属性强;柴胡皂苷a在0.513～3.078μg范围内线性关系良好（r=0.9999）,平均回收率为99.5%（RSD=0.95%）。结论所建立的方法准确可靠、重复性好,可有效控制艾可合剂的质量。
|
| 关 键 词： | 艾可合剂 质量标准 柴胡皂苷a 薄层色谱法 高效液相色谱法 |
Study on the quality standards of Aike mixture |
| |
| PAN Xu-dong,HUANG Yan,LIN Tao,LIN Xiong,ZHANG Min-jian.Study on the quality standards of Aike mixture[J].Strait Pharmaceutical Journal,2010,22(6):65-67. |
| |
| Authors: | PAN Xu-dong HUANG Yan LIN Tao LIN Xiong ZHANG Min-jian |
| |
| Institution: | 1.People＇s hospital of Fujian TCM Fuzhou 350004;2.Fujian provincial hospital of Dermatology STD,Fuzhou 350009,China) |
| |
| Abstract: | OBJECTIVE To establish the quality standards of Aike mixture.METHODS We identified the ingredient of Root of Herbaceous peony,Chishao and Citrus aurantium in Aike mixture by TLC;we detected the content of Saikosaponin-A in Aike mixture by HPLC,used gradient elution and the mobile phase was Acetonitrile-water.RESULTS The way of TLC had a good separation and specificity and Saikosaponin-A had a good linear relationship in 0.513～3.078μg（r=0.9999）,the average recovery was 99.5%（RSD=0.95%）.CONCLUSION the way of identification is accurate,reproducible and can be used in the quality control of Aike mixture. |
| |
| Keywords: | Aike mixture Quality standards Saikosaponin-a TLC HPLC |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
