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千里光致肝窦阻塞综合征伴停经1例
引用本文:刘畅,陆海英,程浩,于岩岩. 千里光致肝窦阻塞综合征伴停经1例[J]. 传染病信息, 2017, 30(4). DOI: 10.3969/j.issn.1007-8134.2017.04.016
作者姓名:刘畅  陆海英  程浩  于岩岩
作者单位:1. 100034,北京大学第一医院感染疾病科;100142,北京大学医学部临床肿瘤学院;2. 北京大学第一医院感染疾病科,100034
基金项目:国家十二五科技重大专项资助项目
摘    要:
肝窦阻塞综合征(hepatic sinusoidal obstruction syndrome,SOS)是一种少见的肝脏血管性疾病,含吡咯烷生物碱的植物为其常见致病因素,严重者可出现致命性多器官功能衰竭。由于SOS早期症状不典型,发病机制复杂,缺乏特效的治疗手段,目前误诊率高、预后较差。本文对1例千里光所致SOS伴停经病例进行报道,并回顾相关文献,为临床防治药物性肝血管损伤提供参考。

关 键 词:肝窦阻塞综合征  病例报告  千里光  停经

A case of hepatic sinusoidal obstruction syndrome with amenorrhea induced by senecio
LIU Chang,LU Hai-ying,CHENG Hao,YU Yan-yan. A case of hepatic sinusoidal obstruction syndrome with amenorrhea induced by senecio[J]. Infectious Disease Information, 2017, 30(4). DOI: 10.3969/j.issn.1007-8134.2017.04.016
Authors:LIU Chang  LU Hai-ying  CHENG Hao  YU Yan-yan
Abstract:
Hepatic sinusoidal obstruction syndrome (SOS) is one of the rare liver vascular diseases. Pyrrolizidine alkaloids is the common pathogenic factor. Despite its relatively low incidence, some cases evolve to severe multi-organ failure. Due to atypical early symptoms, complex pathogenesis and lack of effective treatment, the misdiagnosis rate of SOS is high and the prognosis is poor. This paper reports a case of SOS with amenorrhea caused by senecio, and provides a reference for clinical prevention and treatment of drug-induced hepatic vascular injury.
Keywords:hepatic sinusoidal obstruction syndrome  case report  senecio  amenorrhea
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