精索静脉曲张患者的减数分裂分析

目的：探讨造成精索静脉曲张患者的生育力减弱的机理。方法：对５４例精索静脉曲张患者的睾丸作活检减数分裂分析，对其２９例同时作精液标本的减数分裂分析。结果：５４例患者睾丸活检减数分裂分析阻滞在粗线期４５例，单价体６例，多价体２例，正常减数分裂１例。其中２９例患者睾丸活检、精液标本减数分裂分析阻滞在粗线期２８例，单价体１例，两者结果一致。结论：精索静脉曲线患者的生育力减弱大多受染色体不育效应的影响。

A Study of Meiosis in 54 Cases of Varicocele

Objective:To explore the mechanism leading to reduced productivity by a study of meiosis in cases of varicocele.Methods:Analyses were made of meiosis for the testicular biopsy of 54 cases of varicocele and for the semen samples from 29 of them as well.Results:Among the 54 cases there were 45 cases with meiotic arrest in pachytene stage, 6 univalent cases, 2 multi valent cases and 1 case with normal meiosis. Among the 29 cases there were 28 cases with meiotic arrest in pachytene stages and one univalent case,with both analyses having the same results.Conclusion:A study of meiosis by tesiticular biopsy can be used as an important diagnostic index for the disease,and analyses of meiosis for testicular biopsy can be replaced by analyses of meiosis for semen samples so as to show the similar dynamic conditions for the production of sperms. It is concluded that the mechanism of reduced productivity is mostly affected by sterility of chromosome.