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| 乙肝疫苗初免失败婴儿再免疫方法研究 | |
| 引用本文： | 陈其龙,陶志华,陆飞越,姚凤燕,王建华. 乙肝疫苗初免失败婴儿再免疫方法研究[J]. 浙江预防医学, 2004, 16(10): 4-5 |
| 作者姓名： | 陈其龙 陶志华 陆飞越 姚凤燕 王建华 |
| 作者单位： | 平湖市痰病预防控制中心,浙江,平湖,314200 |
| 摘 要： | 目的探索乙肝疫苗初次全程免疫失败婴儿的再免疫方法.方法对乙肝疫苗全程免疫后乙肝病毒表面抗体(抗-HBs)和乙肝病毒表面抗原(HBsAg)均阴性的144名婴儿,随机分成5组,1组为对照组,其余4组分别采用不同的再免疫方法,观察再免成功率.结果抗-HBs总阳转率为93.79%,抗-HBs几何平均滴度(GMT)为546.97mIU/ml,各组抗-HBs阳转率分别为87.88%、90.91%、100%、96.88%;各组GMT分别为475.34mIU/ml、658.65mIU/ml、625.18mIU/ml、455.90mIU/ml.结论乙肝疫苗初免失败婴儿,再免成功率达93.79%. |
| 关 键 词： | 乙肝疫苗 抗-HBs 再免疫 |
| 文章编号： | 1007-0931(2004)10-0004-02 |
| 修稿时间： | 2004-04-13 |
An Investigation for Reimmunization Method in Infants Who Failed in Primary Hepatitis B Vaccination |
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| CHEN Qi long,TA Zhi hua,LU Fei yue,et al.. An Investigation for Reimmunization Method in Infants Who Failed in Primary Hepatitis B Vaccination[J]. Zhejiang Journal of Preventive Medicine, 2004, 16(10): 4-5 | |
| Authors: | CHEN Qi long TA Zhi hua LU Fei yue et al. |
| Affiliation: | CHEN Qi long,TA0 Zhi hua,LU Fei yue,et al. |
| Abstract: | Objective To explore the reimmunization method in infants who failed in primary hepatitis B vaccination.Methods 144 infants who failed in first full course Hepatitis B vaccination (both HBsAg and anti HBs were negative) were enrolled in this study, and they were randomly divided into 5 groups (1 control group and 4 treatment groups with different reimmunization method).Results There were 93 79% infants whose anti HBs became positive, and the geometric mean titer (GMT) of anti HBs was 546 97 mlU/ml. In 4 treatment groups, the positive rates of anti HBs were 87 88%, 90 91%, 100% and 96 88%, respectively.Conclusions 93 79% infants can gain immunity from reimmunization for infants who failed in primary hepatitis B vaccination. |
| Keywords: | GMT |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |