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Yellow nail syndrome associated with thiol compound therapy for rheumatoid arthritis. Two case reports
Authors:Lehuédé Gaëlle  Toussirot Eric  Despaux Jacques  Michel Fabrice  Wendling Daniel
Affiliation:1. Department of Neurology in Zabrze, Medical University of Silesia, 3-go Maja St. 13-15, Zabrze 41-800, Poland;2. Department of Biochemistry and Cell Biology, Faculty of Biology and Agriculture, University of Rzeszów, Zelwerowicza St. 4, 35-601 Rzeszów, Poland;3. Department of Thoracic Surgery, SMDZ in Zabrze, Medical University of Silesia, 3-go Maja St. 13-15, Zabrze 41-800, Poland;4. Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska St. 141/143, 90-236 Lodz, Poland
Abstract:Yellow nail syndrome is characterized by ungual dystrophy, lower limb lymphedema, and pleural effusions or bronchiectasis. Rheumatoid arthritis is the autoimmune disorder most often associated with yellow nail syndrome. We report two new cases of yellow nail syndrome in patents receiving thiol compound therapy for rheumatoid arthritis. Eight similar cases have been reported since 1979, suggesting a possible causative effect of this class of drugs.
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