鲍曼不动杆菌和洛菲不动杆菌的医院感染情况及耐药性分析

目的了解鲍曼不动杆菌和洛菲不动杆菌的医院感染和细菌耐药情况。方法收集2016年1月1日至2018年12月31日该院临床标本中分离的鲍曼不动杆菌和洛菲不动杆菌,并对标本来源、分布和药敏试验结果进行分析。结果186株鲍曼不动杆菌来源科室主要分布于呼吸内科、康复医学科、神经内科、肾内科和内分泌科,标本以痰液和中段尿为主,对替卡西林/克拉维酸、哌拉西林/他唑巴坦、阿米卡星、头孢他啶、环丙沙星、头孢吡肟和庆大霉素的耐药率分别为26.03%、24.76%、22.86%、18.70%、18.70%、18.20%和16.60%。51株洛菲不动杆菌来源科室主要分布于呼吸内科、泌尿外科、神经内科、肾内科和康复医学科,标本以痰液和中段尿为主,对头孢他啶、环丙沙星、亚胺培南、头孢吡肟、替卡西林/克拉维酸、美罗培南和庆大霉素的耐药率分别为24.00%、22.00%、18.00%、18.00%、15.62%、14.00%和10.00%。结论两种不动杆菌都主要分离于老年男性的呼吸道标本,二者的耐药率均不高,洛菲不动杆菌的总体耐药率低于鲍曼不动杆菌,但是耐碳青霉烯类抗菌药物的洛菲不动杆菌的检出率高于耐碳青霉烯类抗菌药物的鲍曼不动杆菌,需要引起重视。

Hospital infection situation and drug resistance analysis of Acinetobacter baumannii and Acinetobacter lwoffii

Objective To understand the nosocomial infection and bacterial drug resistance situation of Acinetobacter(A.)baumanniiandAl.woffii.Methods ThestrainsofA.baumanniiandstrainsofAl.woffii isolated from clinical samples in this hospital from 1 st Jan.2016 to 31 st Dec.2018 were collected.The specimen source,distribution and drug susceptibility test results were analyzed.Results The source departments of 186 strains of A.baumannii were mainly distributed in the departments of respiratory medicine,rehabilitation medicine,neurology,nephrology and endocrine,the specimens were dominated by sputum and urine,their resistant rates to ticarcillin/clavulanate,piperacillin/tazobactam,amikacin,ceftazidime,ciprofloxacin,cefepime and gentamicin were 26.03%,24.76%,22.86%,18.70%,18.70%,18.20%and 16.60%respectively;the source departments of 51 strains of A.lwoffii were mainly distributed in the departments of respiratory medicine,urology surgery,neurology,nephrology and rehabilitation medicine;the specimens were mainly sputum and urine;their resistant rates to ceftazidime,ciprofloxacin,imipenem,cefepime,ticarcillin/clavulanic,meropenem and gentamicin were 24.00%,22.00%,18.00%,18.00%,15.62%,14.00%and 10.00%respectively.Conclusion The two species of Acinetobacter are mainly separated from the respiratory tract specimens of elderly males.Their drug resistance rate is not high.The overall resistance rate of A.lwoffii is lower than that of A.baumannii,but the detection rate of carbapenem resistant A.lwoffii is higher than that of carbapenem resistant A.baumannii,which needs to pay attention to.