MPV、NLR、MLR与急性胰腺炎的相关性研究

目的探讨平均血小板体积(MPV)、中性粒细胞/淋巴细胞比值(NLR)、单核细胞/淋巴细胞比值(MLR)与急性胰腺炎(AP)的相关性。方法选取该院AP确诊患者110例为病例组,选取同期的体检健康者110例为对照组,对两组首次血常规检测结果中的MPV、NLR、MLR进行比较,采用Spearman相关分析各指标间的相关性,并绘制受试者工作特征曲线(ROC曲线)分析各指标对AP的诊断价值。结果两组MPV、NLR、MLR差异有统计学意义(P<0.05);Spearman相关分析显示,MPV、NLR、MLR与白细胞(WBC)、中性粒细胞(NEUT)、单核细胞(MON)水平均呈正相关(P<0.05);ROC曲线分析显示,MPV、NLR、MLR联合检测诊断价值最佳。结论 MPV、NLR和MLR联合检测可作为AP实验室快速诊断的参考方法。

Study on the relationship between MPV,NLR,MLR and acute pancreatitis

Objective To investigate the relationship between mean platelet volume(MPV),neutrophil to lymphocyte ratio(NLR),monocyte to lymphocyte ratio(MLR)and acute pancreatitis(AP).Methods A total of 110 patients diagnosed with AP in the hospital were selected as the case group,and 110 healthy physical examinees were selected as the control group.MPV,NLR and MLR in the first blood routine items of the two groups were compared.Spearman correlation was used to analyze correlations between the indicators.And receiver operating characteristic(ROC)curve was drawn to analyze the value of the indicators in diagnosis of AP.Results There were significant differences in MPV,NLR and MLR between the two groups(P<0.05).Spearman correlation analysis showed that MPV,NLR and MLR were positively correlated with leukocytes,neutrophils and monocytes(P<0.05).ROC curve analysis showed that the combined detection of MPV,NLR and MLR had the best value in the diagnosis of AP.Conclusion The combined detection of MPV,NLR and MLR can be used as a reference method for rapid laboratory diagnosis of AP.