| 头孢吡肟治疗下呼吸道感染的临床疗效评价 |
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| 引用本文： | 孙书明,吴丽桂,金盈,孟立萍,于雷,沈国锋.头孢吡肟治疗下呼吸道感染的临床疗效评价[J].中国新药与临床杂志,2000,19(3):177-180. |
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| 作者姓名： | 孙书明 吴丽桂 金盈 孟立萍 于雷 沈国锋 |
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| 作者单位： | 上海医科大学,附属金山医院,上海,200540 |
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| 摘 要： | 目的 :评价头孢吡肟治疗下呼吸道感染的临床疗效。方法 :6 8例病人 ,分为治疗组 36例和对照组 32例 ,分别应用头孢吡肟和头孢他啶 ,剂量均为每次 2 g ,q12h ,静脉滴注给药 ,疗程 8.2d±s 2 .6d。结果 :头孢吡肟和头孢他啶的临床有效率分别为94 %和 91% ,细菌清除率为 93%和 85% ,均无明显不良反应。结论 :头孢吡肟可作为治疗下呼吸道感染有效和安全的抗生素
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| 关 键 词： | 头孢吡肟 头孢他啶 呼吸道感染 微生物敏感试验 药物评价 |
Evaluation of clinical therapeutic effect of cefepime in treating lower repiratory tract infections |
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| SUN Shu-Ming,WU Li-Gui,JIN Ying,MENG Li-Ping,YU Lei,SHEN Guo-Feng.Evaluation of clinical therapeutic effect of cefepime in treating lower repiratory tract infections[J].Chinese Journal of New Drugs and Clinical Remedies,2000,19(3):177-180. |
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| Authors: | SUN Shu-Ming WU Li-Gui JIN Ying MENG Li-Ping YU Lei SHEN Guo-Feng |
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| Abstract: | AIM: To evaluate the efficacy of cefepime in the treatment of the lower respiratory tract infections. METHODS: Sixty eight patients were divided into two groups: cefepime group (36 patients) and ceftazidime group (32 patients). The above test and the control groups received cefepime and ceftazidime respectively, 2 g, iv, q 12 h for 8.2 d± s 2.6 d. RESULTS: The overall effective rates of cefepime and ceftazidime were 94 % and 91 %, respectively. The bacterial clearance rates were 93 % and 85 %, respectively. Both were without obvious adverse reactions. CONCLUSION: Cefepime is a safe and potent antibacterial agent in the treatment of the lower respiratory tract infections. |
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| Keywords: | cefepime ceftazidime respiratory tract infections microbial sesitivity tests drug evaluation |
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