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Sequential therapy with caspofungin and fluconazole for Candida albicans infection |
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| Authors: | Barchiesi Francesco Spreghini Elisabetta Baldassarri Isabella Marigliano Anna Arzeni Daniela Giannini Daniele Scalise Giorgio |
| Affiliation: | Istituto di Malattie Infettive e Medicina Pubblica, Università Politecnica delle Marche, Azienda Ospedaliera Umberto I, Via Conca, 60020, Torrette di Ancona, Ancona, Italy. l.infettive@ao-umbertoprimo.marche.it |
| Abstract: | A sequential therapy of caspofungin (CAS) and fluconazole (FLC) administration for treatment of Candida albicans infection was investigated. Treatment with CAS followed by FLC was as effective as CAS treatment given alone for the same duration. Our data suggest that switching from CAS to FLC is a potentially explorable therapeutic option for treatment of systemic candidiasis. |
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