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A型肉毒毒素治疗下肢痉挛型脑性瘫痪的疗效分析
引用本文:王雅洁,高宝勤,韩仰同,杨伟力,梁京滨,雷艳芬,俞亚珍,耿改芹.A型肉毒毒素治疗下肢痉挛型脑性瘫痪的疗效分析[J].中国组织工程研究与临床康复,2001,5(19):44-45.
作者姓名:王雅洁  高宝勤  韩仰同  杨伟力  梁京滨  雷艳芬  俞亚珍  耿改芹
作者单位:首都医科大学附属天坛医院,
摘    要:目的研究A型肉毒毒素(BotulinumToxicA,BTX-A)治疗儿童痉挛型脑性瘫痪的疗效。方法对45例痉挛型脑瘫的患者进行前瞻性研究,在下肢痉挛的肌肉内注射BTX-A,观察治疗前后的肌张力及体能评价分数量表(PhysicalRatingScale,PRS),疗效持续时间及不良反应。结果治疗前与治疗后2周肌张力、治疗后4周PRS相比均具有显著性差异(P<0.05)。结论BTX-A治疗儿童痉挛型脑性瘫痪具有明显疗效。

关 键 词:儿童  脑性瘫痪  肉毒毒素  A  治疗
文章编号:1007- 5496(2001)10- 0044- 02
修稿时间:2001年8月10日

The effect of botulinum toxic A to child cerebral palsy
WANG Ya-jie,GAO Bao-qin,HAN Yang-tong,et al..The effect of botulinum toxic A to child cerebral palsy[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2001,5(19):44-45.
Authors:WANG Ya-jie  GAO Bao-qin  HAN Yang-tong  
Institution:WANG Ya-jie,GAO Bao-qin,HAN Yang-tong,et al. Department of Pediatric,Tian Tan Hospital Capital Medical Univerisity,Beijng 100050,China
Abstract:Objective To study the effect of BTX-A to child cerebral palsy by injecting in spastic muscles. Method 45 cases were injected in spastic muscles with BTX-A. We observed the tone and PRS before therapy and the 2 week tone and the 4 week PRS after therapy. Result The tone before therapy and the 2 week tone after therapy had the significant difference, so was PRS before therapy and the 4 week PRS after therapy.Conclusion BTX-A is significantly effective to child spastic cerebral palsy.
Keywords:child  cerebral palsy  botulinum toxic A  therapy
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