结构方程模型在中医临床疗效评价中的应用

目的 通过收集、整理2005～2008年间在四川康骨医院住院治疗的股骨头坏死患者调查表,分析和评价"针刀加纯中药治疗股骨头缺血性坏死"的真实疗效.方法 依据赵德伟1996年制定的<成人股骨头坏死修复与再造疗效评定标准>,评价受试者在疼痛强度、行走距离、关节活动度、X线片四个指标上的改善效果.结果 单因素分析显示该治疗方法有效(P<0.05),但有些现象无法得到合理的专业解释;通过结构方程模型建立因果通径,可很好地解决这一问题.结论 通过结构方程模型方法拟合因果通径模型,对混杂因素有更好的控制,对疗效的评价更加可靠.

Application of Structural Equation Model in the Study of Therapeutic Effect of Chinese Medicine

Objective The questionaires of the ONFH aegers who were hospitalized in Kanggu hospital,during 2005-2008 ,were collect-ed to evaluate the therapeutic effects of acupotomy by proper statistical methods. Methods Four indexes according to the criteria of Therapeutic effect of adult ONFH recovery and reconstruction (ZHAO Dewei, 1996) were measured to evaluate the effect of the treatment. Results Monofac-torial analysis showed that the treatrnent was effective,but some phenomena could not be correctly explined in specialized field. This problem was re-solved appropriately by structural equation model(SEM). Conclusion By the method of SEM, the confounding factors could be better controlled and the evaluation was more reliable.