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Protective effect of yacon leaves decoction against early nephropathy in experimental diabetic rats
Authors:Stella M. Honoré  ,Wilfredo M. Cabrera,Susana B. Genta,Sara S. Sá  nchez
Affiliation:Dpto. Biología del Desarrollo, INSIBIO – Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad Nacional de Tucumán (CONICET-UNT), Chacabuco 461, T4000ILI San Miguel de Tucumán, Argentina
Abstract:
Nephropathy is the most common cause of morbidity and mortality in diabetic patients. Prevention of this complication has a major relevance. Smallanthus sonchifolius (yacon) leaves have been shown to ameliorate hyperglycemia in streptozotocin-induced diabetic rats. We examined the beneficial effects of yacon leaves decoction on diabetic nephropathy and explored the possible underlying action mechanism.
Keywords:Diabetes   Kidney   Yacon   TGF/Smad signaling
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