Protective effect of yacon leaves decoction against early nephropathy in experimental diabetic rats |
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Authors: | Stella M. Honoré ,Wilfredo M. Cabrera,Susana B. Genta,Sara S. Sá nchez |
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Affiliation: | Dpto. Biología del Desarrollo, INSIBIO – Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad Nacional de Tucumán (CONICET-UNT), Chacabuco 461, T4000ILI San Miguel de Tucumán, Argentina |
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Abstract: | Nephropathy is the most common cause of morbidity and mortality in diabetic patients. Prevention of this complication has a major relevance. Smallanthus sonchifolius (yacon) leaves have been shown to ameliorate hyperglycemia in streptozotocin-induced diabetic rats. We examined the beneficial effects of yacon leaves decoction on diabetic nephropathy and explored the possible underlying action mechanism. |
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Keywords: | Diabetes Kidney Yacon TGF/Smad signaling |
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