| 单用卡马西平治疗部分型癫痫的首次血药浓度监测 |
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| 引用本文： | 李洪亮,王利,赵卫兵,杜俊秋.单用卡马西平治疗部分型癫痫的首次血药浓度监测[J].临床和实验医学杂志,2006,5(10):1583-1584. |
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| 作者姓名： | 李洪亮 王利 赵卫兵 杜俊秋 |
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| 作者单位： | 淮安市第三人民医院,江苏,淮安,223001 |
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| 摘 要： | 卡马西平(CBZ)是常用抗痫药之一,是治疗部分型癫痫的一线首选药物。其疗效与其血药浓度密切相关,但其毒副作用较大,个体差异大,又具药酶自身诱导作用。因此,有必要在血药浓度监测下个体化用药。1资料与方法1.1一般资料病例来源于我院药检室2003年3月至2005年12月作血药浓度监测
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| 关 键 词： | 卡马西平 癫痫 血药浓度 |
| 收稿时间： | 08 8 2006 12:00AM |
| 修稿时间： | 2006年8月8日 |
Test the first bloocl drug concentration monitoring in patients with partial seizure dpilepsy treated by carbamazepine |
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| LI Hong - liang, WANG Li,ZHAO Wei- bing ,et al..Test the first bloocl drug concentration monitoring in patients with partial seizure dpilepsy treated by carbamazepine[J].Journal of Clinical and Experimental Medicine,2006,5(10):1583-1584. |
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| Authors: | LI Hong - liang WANG Li ZHAO Wei- bing |
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| Abstract: | Objective To test the carbamazepine concentration in patients with partial seizure epilepsy and offer gists for clinical therapy . Methods 126 cases of carbamazepine concentration in patients with partial seizure epilepsy were examined using high efficiency liquid chromatography method and adjust blood drug concentration according to curative effect. Results The effective rate of using carbamazepine in partial seizure epilepsy alone is 72.2%. Conclusion Blood drug concentration monitoring is advantage of improving safety, availability and rationality of cure to epilepsy , And it can reduce side effect and expenditure. |
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| Keywords: | Carbamazepine Epilepsy Blood drug concentration monitoring |
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