Abstract: | Objective: To explore the mechanism of "Neiguan"(PC6) electroacupuncture in improving acute heart ischemia.Methods: Thirty-two healthy New Zealand rabbits were divided into 4 groups: normal group, sodium chloride group, model group and acupuncture group.Heart ischemia was induced in the rabbits by means of PPI auditive vein injection.We used the technique of microdialysis and inductively coupled plasma optical emission spectroscopy, and collected the extracellular fluid in the point Neiguan(PC6).In the mean time acupuncture of Neiguan was performed.The changes of concentration of ionized calcium in extracellular fluid of Neiguan were observed.Results: The concentrations of ionized calcium of the model group and the acupuncture group were decreased compared with the normal group(P0.05).After acupuncture the concentration of ionized calcium were increased compared with the model group(P0.05), showing that Neiguan electroacupuncture can increase the concentration of ionized calcium.Conclusion: The mechanism of Neiguan(PC6) electro-acupuncture in improving acute heart ischemia is associated with the change of concentration of ionized calcium in extracellular fluid of Neiguan(PC6). |