53例小于40岁的冠心病病人发病特点及危险因素分析

目的:探讨≤40岁的冠心病患者的临床、造影、危险因素特点。方法:总结53例年龄≤40岁(青年组)和59例年龄>60岁(老年组)住院经冠脉造影确诊为冠心病病人的临床资料。将两组病人的临床特点、冠脉造影结果及冠心病的危险因素进行对比。结果:青年组典型胸痛,冠心病家族史,吸烟史以及男性患者比例均明显高于老年组。青年组血甘油三酯高于老年组[(2.71±1.12)mmol/L　vs(2.02±1.24)mmol/L](P<0.01)。冠脉造影示青年组以单支病变多见,多累及前降支且侧支循环较少。结论:青年冠心病患者发病迅速,症状典型,男性比例高,因此有冠心病阳性家族史的青年男性更应积极控制各种冠心病危险因素。

Analysis of Character and Risk Factors on Coronary Artery Disease in 53 Patients at or under 40 Years

Objective: To study the character of onset, angiographies, and risk factors in patients with coronary artery disease (CMD) at or under 40 years. Methods: Data of onset, angiography, and risk factor of CAD were analyzed in 53 patients at or under 40 years (young group) and 59 patients older than 60 years (old group). All patients were diagnosed of CAD by cardiac cathelerization. Results: Typical chest pain, CAD family history, smoking, and male were more significant in young group than those in old group. Level of triglyceride was higher in young group (2.71 + 1.12)mmol/L than that in old group (2.02 + 1.24)mmol/L (P<0.01). Single vessel disease had a higher proportion in young group than that in old group, and the left anterior descending involved with less collateral circulation. Conclusion: More attention should be paid to control the risk factors in young male patients with CAD family history because of their rapid onset, typical manifestation, and higher proportion of male.