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| 枸杞在保护大鼠视网膜光损伤中作用的研究 | |
| 引用本文： | 刘娜,李子良,曹安民. 枸杞在保护大鼠视网膜光损伤中作用的研究[J]. 中华眼底病杂志, 1995, 11(1): 31-33 |
| 作者姓名： | 刘娜 李子良 曹安民 |
| 作者单位： | 宁夏医学院附属医院眼科，徐州眼病防治研究所，美国伊里诺州大学眼科中心 |
| 摘 要： | 用254.75cd的荧光灯作为光源，照射大鼠视网膜，建立光损伤动物模型。对照组大鼠视网膜光镜下见锥体、杆体细胞层破坏严重，外核层紊乱，细胞核数目明显减少。电镜下，外节破坏溶解、空泡形成，内节肿胀，视网膜色素上皮(RPE)坏死；口服枸杞的治疗组则表现为锥体、杆体层轻度破坏，外核层排列较整齐。细胞数日接近正常。表明枸妃对大鼠视网膜锥体、杆体层，外核层和RPE有明显的保护作用。（中华眼底病杂志，1995，11：31-33） |
| 关 键 词： | 枸杞 光损伤 视网膜 大鼠 电镜 中医药疗法 |
| 收稿时间： | 1994-01-28 |
| 修稿时间： | 1994-06-04 |
A RESEARCH OF LYCIUM BARBARUM L. IN RESCUE OF RETINA FROM PHOTIC INJURY IN RATS |
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| Liu Na,Li Ziliang,Tso MOM. A RESEARCH OF LYCIUM BARBARUM L. IN RESCUE OF RETINA FROM PHOTIC INJURY IN RATS[J]. Chinese Journal of Ocular Fundus Diseases, 1995, 11(1): 31-33 | |
| Authors: | Liu Na Li Ziliang Tso MOM |
| Affiliation: | Dept. Ophthalmology.Teaching Hospital of Ningxia Medical College,Yinchuan 750004 |
| Abstract: | The induction of photic retinal injury model was carried out by exposing rats to intense fluoresence light(250 foot-candle) for 24 hours. Lycium barbarum L.was fed to treated rats before,during and after light exposure. We found that rods and cones of retina in control rats were severely injurcd. The number of nucleus in ONL was significantly decreased,and the degeneration and necrosis of RPE was also noted. In treat rats, the rods and cones were nearly normal The number of photoreceptor nucleus was slightly decreased. The results of morphologic and morphometric studies showed that Lycium barbarum L.could proserve the outer nuclear layer,rods and cones and RPE cells significantly.（Chin J Ocul Fundus Dis,1995,11: 31-33） |
| Keywords: | Lycium barbarum L Retina Photic injury |
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