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Therapeutic effect of Oenanthe javanica flavone on streptozotocin-induced diabetic mice
Authors:Xin-boYANG Zheng-mingHUANG Wen-binCAO Hong-yanCHEN Jian-huaWANG
Affiliation:DepartmentofPharmacology,ChinesePLA301HospitaiofPLA,Beijing100853,China
Abstract:
AIM: To observe the therapeutic and preventive effects of Oenanthejavanica flavone (OjF) on streptozotocin induced diabetic mice. METHODS: Mice were given injected ip with streptozotocin (STZ) 150 mg/kg to induce diabetic model. The diabetic mice were given OjF 50 mg/kg, 100 mg/kg,ig. The blood samples were taken at 1, 5 h after treatment for observing the effects of OjF. After the latter time point (5 h) the blood were taken by exsaguinating, then the serum was centrifugated and
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