PDE3 inhibition by cilostazol attenuated developmental hyperserotonemia induced behavioural and biochemical deficits in a rat model of autism spectrum disorder |
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| Affiliation: | 1. CNS and CVS Lab., Department of Pharmacology, School of Pharmacy, Bharat Institute of Technology, Partapur Bypass, Meerut, Pin-250103, Uttar Pradesh, India;2. School of Pharmacy, Bharat Institute of Technology, Partapur Bypass, Meerut, Pin-250103, Uttar Pradesh, India;3. CNS Pharmacology, Conscience Research, Pocket F-233, B, Dilshad Garden, Delhi 110095, India;4. Department of Pharmacology, Amity Institute of Pharmacy, Amity University Uttar Pradesh, A-Block, Ground Floor, Sector-125, Noida - 201303, Uttar Pradesh, India |
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| Keywords: | Developmental hyperserotonemia Phosphodiesterase 3 BDNF Neuroinflammation Oxidative stress 5-MT" },{" #name" :" keyword" ," $" :{" id" :" key0035" }," $$" :[{" #name" :" text" ," _" :" 5 – Methoxytryptamine 5-HT" },{" #name" :" keyword" ," $" :{" id" :" key0045" }," $$" :[{" #name" :" text" ," _" :" 5 – Hydroxytryptamine ASD" },{" #name" :" keyword" ," $" :{" id" :" key0055" }," $$" :[{" #name" :" text" ," _" :" Autism Spectrum Disorder BDNF" },{" #name" :" keyword" ," $" :{" id" :" key0065" }," $$" :[{" #name" :" text" ," _" :" Brain derived neurotropic factor CMC" },{" #name" :" keyword" ," $" :{" id" :" key0075" }," $$" :[{" #name" :" text" ," _" :" Carboxy-methyl cellulose CREB" },{" #name" :" keyword" ," $" :{" id" :" key0085" }," $$" :[{" #name" :" text" ," _" :" cAMP response element binding protein DHS" },{" #name" :" keyword" ," $" :{" id" :" key0095" }," $$" :[{" #name" :" text" ," _" :" Developmental hyperserotonemia EPM" },{" #name" :" keyword" ," $" :{" id" :" key0105" }," $$" :[{" #name" :" text" ," _" :" Elevated Plus maze GD" },{" #name" :" keyword" ," $" :{" id" :" key0115" }," $$" :[{" #name" :" text" ," _" :" Gestational Day PND" },{" #name" :" keyword" ," $" :{" id" :" key0125" }," $$" :[{" #name" :" text" ," _" :" Post-natal Day TBARS" },{" #name" :" keyword" ," $" :{" id" :" key0135" }," $$" :[{" #name" :" text" ," _" :" Thiobarbituric acid reactive substance |
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