Photodynamic therapy-a promising treatment of oral mucosal infections |
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| Institution: | 1. Department of Oral Medicine and Radiology, Manipal College of Dental Sciences, Mangalore 575001, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India;2. School of Medicine and Dentistry, Griffith University, Australia;3. Formerly Department of Public Health Dentistry, Manipal College of Dental Sciences, Mangalore 575001, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India;4. Menzies Health Institute Queensland, Griffith University, Australia;1. Department of Dentistry, Laboratório de Pesquisa em Saúde, Hospital Universitário Clemente Faria, Universidade Estadual de Montes Claros (Unimontes), 562 Av. Cula Mangabeira Santo Expedito, Montes Claros, Minas Gerais 39401-001, Brazil;2. Institute of Agricultural Sciences, Universidade Federal de Minas Gerais (UFMG), Montes Claros, Minas Gerais, Brazil;3. Dilson Godinho Hospital, Montes Claros, Minas Gerais, Brazil;1. State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, PR China;2. Emergency Department, State Key Laboratory of Oral Diseases, National Center of Stomatology, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, No. 14, Sec. 3 Renminnan Road, Chengdu, Sichuan 610041, PR China |
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| Abstract: | The treatment of oral mucosal infections is increasingly challenging owing to antibiotic resistance. Therefore, alternative antimicrobial strategies are urgently required. Photodynamic therapy (PDT) has attracted attention for the treatment of oral mucosal infections because of its ability to effectively inactivate drug-resistant bacteria, completely heal clinical infectious lesions and usually offers only mild adverse reactions. This review briefly summarizes relevant scientific data and published papers and discusses the potential mechanism and application of PDT in the treatment of oral mucosal infections. |
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