首发脑卒中患者抑郁危险因素及生存质量分析

目的 探讨脑卒中患者抑郁危险因素,对患者生存质量进行分析.方法 300例脑卒中患者分为抑郁组和非抑郁组,对危险因素和患者生存质量进行分析.结果 ≥45岁患者汉密顿抑郁量表（HAMD）评分为（21.28 ±6.01）分,高于＜45岁患者[（16.09±4.15）分,t=3.64,P=0.02];医疗负担由轻到重依次为（12.53 ±2.96）分、（16.11 ±3.42）分和（24.39±6.11）分（=4.02,P=0.01）.患者有无合并症HAMD评分差异有统计学意义（t=3.96,P=0.01）.对患者抑郁影响因素进行Logistic回归分析,与年龄、医疗负担、合并症和神经功能缺损程度等相关影响因素有关（OR=1.26、1.19、1.24、1.12,P=0.02、0.01、0.01）.抑郁组巴氏指数、简式评分法和神经功能缺损程度分别为（57.19 ±6.27）分、（59.28 ±5.92）分和（21.52 ±4.63）分,与非抑郁组比较,差异有统计学意义（t=4.87、5.46、3.29,P=0.01、0.01、0.02）.结论 首发脑卒中患者抑郁影响因素与年龄、医疗负担、合并症和神经功能缺损程度等有关,抑郁组的生活质量明显低于非抑郁组.

Analysis of the risk factors of depression and life quality in patients with the first stroke

Objective To explore the risk factors of the stroke patients with depression and the life quality.Methods 300 patients with the first stroke were divided into depression group and non depression group.The risk factors of depression and the life quality were analyzed.Results The HAMD score of ≥ 45 years old patients was （21.28 ± 6.01）,which was higher than that of ＜ 45 years old （16.09 ± 4.15） （t =3.64,P =0.02）.Medical burden from light to heavy were（12.53 ± 2.96）,（16.11 ± 3.42） and （24.39 ± 6.11） （t =4.02,P =0.01）.HAMD score without comorbid had significant difference（P =0.01）.Logistic regression analysis showed that the influence factors of depression were associated with age,medical expenditure,complications and the degree of nervous function defect and others（OR =1.26,1.19,1.24,1.12,P =0.02,0.01,0.01）.BI,FM and AS of the depression group were （57.19 ±6.27）,（59.28 ±5.92） and（21.52 ±4.63）,compared with the non depression group,the difference was significant（t =4.87,5.46,3.29,P =0.01,0.01,0.02）.Conclusion The influence factors of depression were age,medical expenditure,complications and neurological deficits.The life quality of depression group was significantly lower than the non depression group.