Can thyroid stimulating hormone levels by TSH (IRMA) predict relapse of thyrotoxicosis following carbimazole treatment? |
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| Authors: | R Wilson C G Semple A M Reid A C Glen J H McKillop J A Thomson |
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| Affiliation: | University Department of Medicine, Royal Infirmary, Glasgow, UK. |
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| Abstract: | Serum thyrotrophin receptor antibody (TRAb) and thyroid stimulating hormone (TSH) (IRMA) levels were measured in 38 patients at one month after the end of a course of carbimazole/T3 therapy for Graves' disease. Despite the increased sensitivity of the IRMA assay a TSH measurement at this stage was found to be of no predictive value, in contrast to estimation of serum TRAb levels which correctly predicted relapse and remission in 90% of patients. |
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