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| 针灸与缺血预适应“第二保护窗” | |
| 引用本文： | 刘密,方剑乔,严洁,常小荣,王超. 针灸与缺血预适应“第二保护窗”[J]. 中华中医药杂志, 2011, 0(5): 954-958 |
| 作者姓名： | 刘密 方剑乔 严洁 常小荣 王超 |
| 作者单位： | 湖南中医药大学针灸推拿学院;浙江中医药大学第三临床医学院 |
| 基金项目： | 国家重点基础研究发展计划(No.2009CB522904);国家自然科学基金项目(No.81072868);浙江省“重中之重”学科(针灸推拿学)科研开放基金资助项目(No.ZTK2010B05);湖南省教育厅重点课题(No.08A048)~~ |
| 摘 要： | 缺血预适应作为诱发细胞自身保护反应的重要机制,对包括心肌细胞在内的各种组织器官均有明显的保护作用,尤其是缺血预适应"第二窗口"保护或延迟性保护的作用较强,时间窗较宽,并有可能通过针灸预处理等手段模拟诱导其保护作用。文章从缺血预适应的信号转导途径的"触发物质-中介物质-效应子"3个环节,总结了针灸与缺血预适应触发物质、针灸与缺血预适应中介物质以及针灸与缺血预适应延迟保护效应的研究进展。 |
| 关 键 词： | 针灸 缺血预适应 治未病 预处理 |
Acupuncture and the second protection window of ischemic preconditioning |
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| LIU Mi,FANG Jian-qiao,YAN Jie,CHANG Xiao-rong,WANG Chao. Acupuncture and the second protection window of ischemic preconditioning[J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2011, 0(5): 954-958 | |
| Authors: | LIU Mi FANG Jian-qiao YAN Jie CHANG Xiao-rong WANG Chao |
| Affiliation: | 1(1College of Acu-Moxibustion and Massage,Hunan University of Chinese Medicine,Changsha 410208,China;2The Third Clinical College of Zhejiang Chinese Medical University,Hangzhou 310005,China) |
| Abstract: | Ischemic preconditioning(IP) was the important mechanism of inducing the cell protective effect on various organs,including cadiocyte.Especially the second protection window of ischemic preconditioning or delayed protection has better effect and longer duration than early period,and it could simulate inducing the protection by acupuncture-pretreatment.Based on the signal transduction pathway of ’trigger-transducer-effector’,this article summarizes progresses in research between acupuncture and triggers,transducers,and effectors. |
| Keywords: | Acupuncture Ischemic preconditioning Treating disease before its onset Pretreatment |
| 本文献已被 CNKI 等数据库收录！ | |