Changes in the ratio between apolipoprotein (a) and lipids in human plasma during interaction with polyclonal sheep antibodies against lipoprotein (a) |
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| Authors: | Chernyad'eva I F Lopata N S Afanasieva O I Pokrovskii S N Kukharchuk V V |
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| Affiliation: | (1) Laboratory of Hemodialysis and Plasmapheresis, A. L. Myasnikov Institute of Cardiology, Russian Research-and-Production Center for Cardiology, Russian Ministry of Health, Moscow |
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| Abstract: | ![]()
Plasma contents of apolipoprotein (a), apolipoprotein B 100, cholesterol, triglycerides, and vitamin E were measured in 2 patients with lipoprotein (a) concentration >100 mg/dl during the interaction with the anti-lipoprotein (a) immunosorbent. Intraindividual heterogeneity of apolipoprotein (a)-containing particles in the plasma was demonstrated. Polyclonal antibodies against lipoprotein (a) immobilized on Sepharose CL-4B more effectively removed free apolipoprotein (a) than complexes containing apolipoproteins B 100, apolipoprotein (a), lipids, and vitamin E. |
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| Keywords: | lipoprotein (a) apolipoprotein (a) apolipoprotein B 100 anti-lipoprotein (a) immunosorbent vitamin E |
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