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Radiation synovectomy with 165Dy-FHMA: lymph node uptake and radiation dosimetry calculations
Authors:M R Zalutsky  P P Venkatesan  R J English  S Shortkroff  C B Sledge  S J Adelstein
Abstract:The lymph node uptake of 165Dy was measured in 25 patients treated by radiation synovectomy via intra-articular injection of 165Dy-ferric hydroxide macroaggregates (FHMA). An average of 0.12% of the injected dose was found in the inguinal lymph nodes 19h post injection. This results in a lymph node of 16.6 rad (166 mGy), a dose significantly less than that reported following radiation synovectomy with other radiocolloids. Dosimetry calculations for the intra-articular injection of 165Dy-FHMA are provided in the appendix.
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