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乙型病毒性肝炎核心抗体阳性对肾移植患者影响的临床研究
引用本文:穆星宇,秦燕,范昱,张芳,王忠.乙型病毒性肝炎核心抗体阳性对肾移植患者影响的临床研究[J].中国血液净化,2009,8(11):615-617.
作者姓名:穆星宇  秦燕  范昱  张芳  王忠
作者单位:上海市交通大学附属第一人民医院肾移植科,上海,200080
摘    要:目的探讨乙型肝炎核心抗体(HBcAb)对于。肾移植患者的影响。方法观察不同乙型病毒性肝炎(乙型肝炎)标志物A组(乙型肝炎表面抗原HBsAg^+,HBcAb^+),B组(HBskg,HBcAb^+),C组(HBsAg-,HBcAb-)]组间肾移植患者肝功能、肾功能等指标间的差异。结果A组肝功能异常发生率52.0%,B组肝功能异常发生率36.8%,C组肝功能异常发生率8.69%,三组间比较均有显著差异。结论肾移植患者合并单纯乙型肝炎核心抗体阳性肝功能异常发生率仍较高。

关 键 词:肾移植  肝功能异常  乙型肝炎病毒

The influence of anti-HBc antibody on patients after renal transplantation
MU Xing-yu,QIN Yan,FAN Yu,ZHANG Fang,WANG Zhong.The influence of anti-HBc antibody on patients after renal transplantation[J].Chinese Journal of Blood Purification,2009,8(11):615-617.
Authors:MU Xing-yu  QIN Yan  FAN Yu  ZHANG Fang  WANG Zhong
Institution:. (Department of Renal Transplantation, Shanghai Jiaotong University Affiliated First People's Hospital, Shanghai 200080, China)
Abstract:Objective To study the influence of anti-hepatitis B core antigen antibody (HBcAb) on renal transplantation patients. Methods Patients were divided into 3 groups based on the markers for hepatitis B virus infection: Group A (HBsAg+ and HBcAb+), Group B (HBsAg- and HBcAb+), and Group C (HBsAg- and HBcAb-). Liver damage and kidney function were analyzed among the 3 groups after renal transplantation. Results The incidence of liver damage was 52.0% in group A, 36.8% in group B, and 8.69% in group C. Significant differences were found among the 3 groups. Conclusions Liver damage is frequently seen in patients with positive HBcAb after transplantation.
Keywords:Renal transplantation  Liver damage  Hepatitis B virus
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