新型冠状病毒奥密克戎变异株感染轻型患者的中医证候特点

目的 ：分析本土新型冠状病毒（新冠）变异株感染轻型患者的中医证候特点，为该病的防治提供临床依据。方法：选取2022年3月24日—4月24日上海交通大学医学院附属瑞金医院北部院区以及嘉荷新苑方舱收治的感染新冠奥密克戎变异株轻型患者为研究对象，共计纳入188例。通过问卷星进行基本情况、疾病史、流行病学史、中医证候和转阴天数等的收集，分析患者的一般情况、舌苔脉象辨证分型，及不同证型转阴时间。结果：轻型患者基础体质均较好，合并各种基础疾病的比例均低于20%。根据舌象、舌形、舌苔观察，发现不同舌形转阴中位时间差异有统计学意义（P<0.01）。寒湿郁肺证占38.8%，邪热犯肺证占34.5%，湿遏肺卫证占23.4%，其中寒湿郁肺证及邪热犯肺证为感染奥密克戎变异株轻型患者的主要证型。各证型转阴中位天数差异无统计学意义（P>0.05）。结论：上海本土感染新冠奥密克戎变异株发病以疫毒兼挟寒湿之邪致病为主，其中寒湿郁肺证最多见。

Characteristics of traditional Chinese medicine syndromes in mild cases of coronavirus Omicron variant infection

Objective: To characterize the traditional Chinese medicine (TCM) syndromes of mild corona virus di-sease 2019(COVID-19) cases infected with Omicron variant for better prevention and treatment of COVID-19 infection. Methods A total of 188 mild covid -19 patients infected with Omicron variant infection in the northern section of Ruijin Hospital affiliated to Shanghai Jiao Tong university school of medicine and Jiahe Xinyuan shelter from March 24 through April 24, 2022 were enrolled, the tongue manifestation features, basic information, TCM syndrome and the time of negative turning were collected by the questionnaires. Results The mild cases were generally in good health status, with less than 20% patients having other major diseases. There was statistical significance in the median time of turning negative among different tongue shapes. The tongue coating indicated that the syndrome of cold-dampness stagnating, of evil-heat accumulating and dampness blocking in the lung pattern accounted for 38.8%, 34.5% and 23.4% of all cases. The syndrome of cold-dampness stagnating in the lung pattern and the syndrome of evil-heat accumulating in the lung pattern were found in majority of patient investigated. It took similar time for patients with different syndrome types to become COVID-19 virus negative (P>0.05). Conclusions The cold dampness was most common among mild COVID-19 patients with Omicron infection, who predominately presented syndrome of cold-dampness stagnating in the lung pattern.