Invasive Streptococcus pneumoniae in France: antimicrobial resistance, serotype, and molecular epidemiology findings from a monthly national study in 2000 to 2002 |
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| Authors: | Decousser Jean-Winoc,Pina Patrick,Viguier Florent,Picot Franc,Courvalin Patrice,Allouch Pierre ColBVH Study Group |
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| Affiliation: | Centre Hospitalier de Versailles André Mignot, Service d'Hygiène Hospitalière, 177 rue de Versailles, 78157 Le Chesnay Cedex, France. JWDECOUSSER@ch-versailles.fr |
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| Abstract: | A study of 257 French invasive pneumococci isolated between 2000 and 2002 showed high rates of nonsusceptibility to penicillin and macrolides (50%), contrasting with a low frequency of resistance to amoxicillin or levofloxacin (<1%) and tolerance to vancomycin (0%). The genetic homogeneity of some serogroups, including serogroup 1, enhanced the risk of epidemiological changes. |
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