71例新生儿溶血病的实验诊断及治疗

目的研究新生儿溶血病的实验诊断及治疗。方法 2000年1月至2009年7月桂林市中心血站采用直接、间接抗人球蛋白法及吸收放散试验对71例新生儿溶血病患者进行实验诊断,并根据实验结果对患儿进行治疗。结果在71例新生儿溶血病患者中ABO新生儿溶血病67例,占94.36%;其中需换血治疗3例,占ABO新生儿溶血病中的4.47%;RH(D)新生儿溶血病4例,占5.64%,均行换血治疗。结论部分ABO新生儿溶血病患者需进行换血治疗,RH(D)新生儿溶血病全部需换血治疗。

Laboratory diagnosis and treatment of 71 cases of neonatal hemolytic disease

Objective To study the laboratory diagnosis and treatment of neonatal hemolytic disease.Methods From Jan.2000 to July 2009,71 cases of neonatal hemolytic disease were diagnosed by the direct and indirect anti-human globulin method and Absorption elution test.The patients were treated based on the diagnoses results.Results Among the 71 cases of neonatal hemolytic disease,67 cases were ABO hemolytic disease of newborns （94.36%）,in which 3 cases needed to exchange transfusion treatment,accounting for 4.47% in ABO hemolytic disease of newborn cases,while 4 cases were RH （D） hemolytic disease of newborn （5.64%） and received blood exchange transfusion.Conclusion Some ABO hemolytic disease of newborn cases need blood exchange transfusion therapy,and all of RH （D） hemolytic disease of newborn cases need blood exchange transfusion therapy.