Polynitroxyl albumin inhibits inflammation and vasoocclusion in transgenic sickle mice期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Polynitroxyl albumin inhibits inflammation and vasoocclusion in transgenic sickle mice

Authors:	Mahaseth Hemchandra Vercellotti Gregory M Welch Thomas E Bowlin Paul R Sonbol Khalid M Hsia Carleton J C Li Ma Bischof John C Hebbel Robert P Belcher John D

Affiliation:	Division of Hematology, Oncology, and Transplantation, Department of Medicine, University of Minnesota, Minneapolis 554455, USA.

Abstract:

Keywords:	AA, ambient air DSFC, dorsal skin-fold chamber dsDNA, double stranded DNA EDTA, ethylenediaminetetraacetate EMSA, electrophoretic mobility-shift assay HEPES, N-2-hydroxyethylpiperazine-N-2-ethanesulfonic acid HR, hypoxia-reoxygenation ICAM-1, intercellular adhesion molecule-1 IV, intravenous, intravenously NF-κB, nuclear factor-κB NADPH, reduced form of nicotinamide adenine dinucleotide phosphate NOX, NADPH oxidase PMSF, phenylmethylsulfonylfluoride PNA, polynitroxyl albumin RBC, red blood cell ROS, reactive oxygen species SCD, sickle-cell disease SDS-PAGE, sodium dodecyl sulfate-polyacrylamide-gel electrophoresis SOD, superoxide dismutase VCAM-1, vascular cell-adhesion molecule-1 XO, xanthine oxidase
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