| 牛磺酸对家兔心肌肌膜和磷脂脂质体脂质过氧化的影响 |
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| 基金项目： | 国家科委“七五”攻关资助项目 |
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| 摘 要： | 在家兔心肌肌膜和人工生物膜脂质体上,牛磺酸显著抑制氧自由基发生系统(FeCl_3和抗坏血酸)所引起的脂质过氧化物丙二醛的增加,其抑制作用呈剂量依赖和时间依赖关系。本结果证实牛磺酸具有抗氧化作用,在膜水平上直接起到自由基清除剂作用。
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| 关 键 词： | 牛磺酸 脂质过氧化 心肌肌膜 脂质体 |
THE EFFECTS OF TAURINE ON LIPID PEROXIDATION OF RABBIT'S MYOCARDIAL SARCOLEMMA AND PHOSPHOLIPID LIPOSOME |
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| Abstract: | In the rabbit's myocardial sarcolemma and artificial biomem-brane-liposomes, the lipid peroxidation caused by free radical gene-arting system ( FeCls & ascorbic acid ) was significantly inhibited by taurine at the concentractions of 5~20 m mol/L, and the inhibition effects of taurine were both dose and time-dependent. The results showed that taurine had an antioxidation effects and served as a scavenger of free radicals at the level of membrane. |
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| Keywords: | Taurine Lipid peroxidation myocardial sarcolemma Liposome |
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