急性肺动脉栓塞患者CT阻塞指数与缺氧严重程度的相关性研究

目的:评价急性肺动脉栓塞患者CT阻塞指数(CTOI)与缺氧严重程度的相关性。方法:对24例急性肺动脉栓塞患者(栓塞组)的CT肺动脉造影(CTPA)资料进行回顾性分析,了解肺动脉CTOI与血氧饱和度(SO2)的相关性;以30例无栓塞的患者作为对照组,了解栓塞患者及无栓塞患者的SO2是否有差异;以SO2值94%为标准,将肺动脉栓塞患者分为缺氧组(<94%)和非缺氧组(≥94%),了解引起缺氧的肺动脉栓塞程度。结果:肺动脉栓塞组和对照组的SO2分别为:(89.96±7.68)%和(97.53±5.26)%,肺动脉栓塞组的SO2明显低于对照组(P<0.05);CTOI与SO2之间呈明显负相关(r=0.45,P=0.03),随着CTOI的增加,SO2降低越明显;肺动脉栓塞患者中,非缺氧组CTOI值的95%可信区间为0%～49.20%,缺氧组CTOI值的95%可信区间为39.88%～100%,CTOI值为40%～50%时,患者处于氧供不足的临界状态。结论:急性肺动脉栓塞患者CTOI与缺氧严重程度具有相关性,SO2值低于94%时,提示肺动脉栓塞超过约50%。

Correlation between obstruction index with CT pulmonary angiography and severity of hypoxia in acute pulmonary embolism

Objective： To evaluate the correlation between CT obstruction index（CTOI）and severity of hypoxia in acute pulmo-nary embolism. Methods： The CT pulmonary angiography（CTPA） of 24 patients （embolism group） with acute pulmonary embol-ism were retrospectively analyzed. Analyzed the correlation of CTOI and blood oxygen saturation（SO2）. 30 patients without pul- monary embolism served as control, compared the SO2 between the embolism group and the control group. 24 patients with acute pulmonary embolism were divided into hypoxia（〈94%）and non-hypoxic group（≥ 94%）, estimated the extent of pulmonary embolism to which could lead to hypoxia. Results： In the embolism group and the control group, the SO2 were 89.96 % 4-7.68% and 97.53%±5.26% respectively. The values of SO2 in the embolism group were significant lower than that in the control group（ P 〈0.05）. There was a negative correlation between CTOI and SO2 （ r=0.45, P=0.03） ,SO2 reduced accompany with the increase of CTOI. The 95% confidence interval of CTOI was 0%-49.20% in non-hypoxic group,and 39.88%-100% in the hypoxic group. Patients were in the critical state when the CTOI value ranged from 40% to 50%. Conclusion：There is a cor-relation between CTOI and hypoxia in the patients with acute pulmonary embolism. It＇s suggested that more than 50% of pul-monary is embolized when the SO, is lower than 94%.