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地奥心血康软胶囊对AMI患者行PCI术后血清细胞凋亡因子及其心功能的影响
引用本文:王冬梅,石蓓,赵然尊,许官学. 地奥心血康软胶囊对AMI患者行PCI术后血清细胞凋亡因子及其心功能的影响[J]. 山东医药, 2011, 51(5): 1-3
作者姓名:王冬梅  石蓓  赵然尊  许官学
作者单位:遵义医学院附属医院,贵州遵义,563003
基金项目:国家自然科学基金资助项目(30860100)
摘    要:
目的探讨地奥心血康软胶囊对急性心肌梗死(AMI)患者血清细胞凋亡因子及其心功能的影响。方法将50例AMI患者随机分为两组,均采用AMI常规治疗;在此基础上,治疗组加服地奥心血康软胶囊,疗程均为8周。观察两组治疗前后血清Fas及其配体sFasL变化,以及心功能指标舒张末期左室前后径、收缩末期左室前后径、左室射血分数变化,并观察药物不良反应。结果与治疗前比较,两组治疗后血清sFas、sFasL均降低、心功能指标均改善(P均〈0.05),但以治疗组血清sFas、sFasL降低明显(P均〈0.05)。结论常规疗法+地奥心血康软胶囊治疗可减少AMI患者的细胞凋亡,改善其心功能,且临床用药安全。

关 键 词:冠状动脉疾病  心肌梗死,急性  地奥心血康软胶囊  细胞凋亡因子

Effect of Diao Xinxuekang soft capsules on heat function and serum apoptotic cytokines in patients with acute myocardial infarction after PCI
WANG Dong-mei,SHI Bei,ZHAO Ran-zun,XU Guan-xue. Effect of Diao Xinxuekang soft capsules on heat function and serum apoptotic cytokines in patients with acute myocardial infarction after PCI[J]. Shandong Medical Journal, 2011, 51(5): 1-3
Authors:WANG Dong-mei  SHI Bei  ZHAO Ran-zun  XU Guan-xue
Affiliation:WANG Dong-mei,SHI Bei,ZHAO Ran-zun,XU Guan-xue(Affiliated Hospital,Zunyi Medical College,Zunyi 563003,P.R.China)
Abstract:
Objective To observe the effect of Diao Xinxuekang soft capsules on heart function and serum level of sFas and sFasL in patients with acute myocardial infarction.Methods Fifty patients with acute myocardial infarction(AMI) were divided into therapy group and control group randomly.The control group was given conventional therapy.The therapy group was given Diao Xinxuekang soft capsules and the conventional therapy.The course of treatment were 8 weeks.The left ventricular pre-and post-diameter in diastasic a...
Keywords:acute myocardial infarction  apoptotic cytokines  Diao Xinxuekang soft capsules  
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