脑梗死伴高同型半胱氨酸血症的危险因素分析

目的 探索脑梗死患者伴发HHcy的危险因素.方法 将144例脑梗死患者分成HHcy组53例和对照组91例,通过比较组别间性别、年龄、烟酒史、血生化、糖化血红蛋白等指标,运用非条件Logistic回归分析此类人群中HHcy的相关因素.结果 性别、吸烟情况、饮酒和糖化血红蛋白进入回归模型,是HHcy的危险因素.结论 脑卒中患者中高同型半胱氨酸血症的危险因素为男性、吸烟饮酒行为、血糖异常.在健康宣教中指导脑卒中患者控制血糖的同时注意监测Hcy浓度差异以预防、纠正HHcy.

Research for risk factors of cerebral infarction patients with hyperhomocysteinemia

Objective To observe the occurrence of hyperhomocysteinemia among patients suffering from cerebral infarction,and explore the possible risk factors.Methods Data of 144 cerebral infarction patients were collected from a tertiary hospital in Tianjin including gender,age,diabetes mellitus,hypertension,smoking,alcoholism,plasma homocysteine,HbAlc and biochemical criterion.Two groups were created as the hyperhomocysteinemia group and the control group based on serum homocysteine levels.Risk factor for hyperhomocysteinemia was analyzed by application of Logistic regression.Results Logistic regression analysis revealed that hyperhomocysteinemia was associated with gender,smoking,drinking and HbAlc levels in patients.Conclusions Male,smoking,drinking and diabetes mellitus were the possible risk factors in cerebral infarction patients.