多原发性肺癌31例分析

目的 探讨多原发性肺癌特点。方法 检索1981年1月－1999年6月在我院手术治疗的肺癌病人4638例,其中31例病理确诊为多原发性肺癌,占0.37％。结果 31例中第一、二原发肺癌以0－65岁发病率最高,分别占64.5%和68.2%。64个原发癌中鳞癌占54.7％。同时癌、异时癌、同时异时癌分别占29％、64.5％及6.5%。X线显示：64个原发癌以周围型多见,占71.9％。Ⅰ～Ⅱ期为84.4％。异时癌第二原发癌术后5年生存率占22.7%(5/22)。结论 多原发性肺癌易发生于老年人,病变多为早期,鳞癌多见,第二原发癌术后5年生存率低。

Analysis of 31 cases with multiple primary lung cancers

Objective　To research the properties of multiple primary lung cancer.Methods　In 4 638 cases of lung cancer patients operated in our hospital from 1981 to 1999,31 cases (0.67%) suffered from multiple primary lung cancer which was proved by pathologic evidence.Results　Patients 50～65 years old had the highest incidence of the first and second cancer with the rate of 64.5% and 68.2% respectively.Squamous carcinoma was account for 54.7% of the 64 primary cancers.The rate of synchronous cancer was 29%,metachronous cancer was 64.5%,and the combination of both were 6.5%.On X-ray,most cancers were peripheral type with a rate of 71.9%.The rate of stage Ⅰ and Ⅱ were 84.4%.The five year survival rate was 22.7% (5/22) after second operation in coexisted cancer group.Conclusions　Multiple primary lung cancers are mostly found in the aged,and usually in early stages.The squamouse carcinoma is more common.The five year survival rate is low after second operation in coexisted cancer group.