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99Tc-MDP治疗强直性脊柱炎的疗效观察
引用本文:黄建敏,潘莉萍,李冬雪,吴炜杰,李会春. 99Tc-MDP治疗强直性脊柱炎的疗效观察[J]. 中华核医学杂志, 2005, 25(3): 174-175
作者姓名:黄建敏  潘莉萍  李冬雪  吴炜杰  李会春
作者单位:050051,石家庄,河北医科大学第三医院核医学科
摘    要:
目的观察^99Tc-亚甲基二膦酸盐(MDP)注射液治疗强直性脊柱炎的疗效。方法对83例强直性脊柱炎患者静脉滴注^99Tc—MDP,观察治疗前后临床和实验室指标及副作用。结果^99Tc—MDP治疗强直性脊柱炎的总有效率为89%,在减轻临床症状,尤其是改善晨僵和关节活动度方面疗效明显,且无明显副作用。结论用^99Tc—MDP,治疗强直性脊柱炎疗效显著,使用安全。

关 键 词:强直性脊柱炎 MDP ^99Tc-亚甲基二膦酸盐 疗效观察 实验室指标 关节活动度 静脉滴注 治疗前后 总有效率 临床症状 疗效显著 副作用 注射液

Therapeutic effect of 99Tc-MDP in the treatment of ankylosing spondylitis
HUANG Jian-min,PAN Li-ping,LI Dong-xue,et al.. Therapeutic effect of 99Tc-MDP in the treatment of ankylosing spondylitis[J]. Chinese Journal of Nuclear Medicine, 2005, 25(3): 174-175
Authors:HUANG Jian-min  PAN Li-ping  LI Dong-xue  et al.
Affiliation:HUANG Jian-min,PAN Li-ping,LI Dong-xue,et al. Department of Nuclear Medicine,The Third Hospital,Hebei Medical University,Shijiazhuang 050051,China
Abstract:
Objective To observe the therapeutic effect of 99Tc-methylene diphosphonic acid (MDP) in the treatment of ankylosing spondylitis (AS). Methods 83 patients with AS were treated with 99Tc-MDP. Clinical manifestation, laboratory examination before and after treatment and side effect were observed. Results The total effect of this treatment was 89%, and the effectiveness of relieving clinical symptom was significant, especially the morning stiffness and limitation of articulation function. No adverse effects was observed. Conclusion The clinical effect of 99Tc-MDP is obvious, and it is safe and no significant adverse reaction.
Keywords:Spondylitis   ankylosing  Yunke  Drug therapy
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