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阻塞性睡眠呼吸暂停综合征与骨质疏松症相关性研究进展
引用本文:房凤凤 刘霖 赵力博 边红艳. 阻塞性睡眠呼吸暂停综合征与骨质疏松症相关性研究进展[J]. 中国骨质疏松杂志, 2023, 0(1): 114-118
作者姓名:房凤凤 刘霖 赵力博 边红艳
作者单位:1.延安大学医学院,陕西 延安 7160002.解放军总医院第二医学中心呼吸与危重症医学科,北京 100853
基金项目:军队保健专项科研课题(19BJZ34);解放军总医院军事医学青年项目(QNC19054);军队装备建设应用研究项目(LB20211A010013)
摘    要:阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea syndrome, OSAS)是常见的临床疾病之一,患病率高,具有潜在致死性,严重威胁到人类健康。骨质疏松症(osteoporosis, OP)被称为静悄悄的杀手,是一种严重危害骨骼健康的慢性疾病。随着我国老龄化进程加速,我国OP患病人数已位于全球第一。《健康中国2030》倡导及早筛查OP,其与OSAS及其合并症的发生发展密切相关。笔者就OSAS与OP的相关研究展开综述,为临床后续深入研究提供依据。

关 键 词:阻塞性睡眠呼吸暂停综合征  骨质疏松  间歇性缺氧  成骨细胞  破骨细胞

Progress of correlation between obstructive sleep apnea syndrome and osteoporosis
FANG Fengfeng,LIU Lin,ZHAO Libo,BIAN Hongyan. Progress of correlation between obstructive sleep apnea syndrome and osteoporosis[J]. Chinese Journal of Osteoporosis, 2023, 0(1): 114-118
Authors:FANG Fengfeng  LIU Lin  ZHAO Libo  BIAN Hongyan
Abstract:Obstructive sleep apnea syndrome (OSAS) is one of the common clinical diseases with a high prevalence, potentially fatality, and a serious threat to human health. Osteoporosis (OP), known as the silent killer, is a chronic disease that seriously endangers bone health. With the acceleration of China''s aging process, the number of OP patients in China has ranked the top in the world. Healthy China 2030 advocates early screening for OP, which is closely related to the occurrence and development of OSAS and its complications. This paper reviews the related research in OSAS and OP to provide a basis for clinical in-depth follow-up research.
Keywords:obstructive sleep apnea syndrome   osteoporosis   intermittent hypoxia   osteoblasts   osteoclasts
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