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艾灸对衰老模型大鼠线粒体DNA含量的影响
引用本文:李丽,赵志恩,徐瑶,李丽红. 艾灸对衰老模型大鼠线粒体DNA含量的影响[J]. 山西中医学院学报, 2007, 8(5): 11-13
作者姓名:李丽  赵志恩  徐瑶  李丽红
作者单位:贵阳医学院,贵州,贵阳,550004;贵阳医学院附属医院,贵州,贵阳,550004
摘    要:
目的:探讨艾灸对衰老模型大鼠肝细胞线粒体DNA含量的影响。方法:将36只SD大鼠随机分为3组:青年对照组、衰老模型组、艾灸治疗组。采用25%D-半乳糖溶液125mg/kg·d-1皮下注射复制衰老大鼠模型,采用紫外分光光度法观察艾灸对衰老模型大鼠肝细胞线粒体DNA含量的影响。结果:与青年对照组比较,衰老模型组大鼠肝细胞线粒体DNA含量明显增加(P<0.05);与衰老模型组比较,艾灸治疗组大鼠肝细胞线粒体DNA含量明显减少(P<0.05)。结论:艾灸可以减少肝细胞线粒体DNA的含量,从而起到延缓衰老的作用。

关 键 词:衰老  艾灸  线粒体DNA含量
文章编号:1671-0258(2007)05-0011-03
修稿时间:2007-06-19

Effect of Moxibustion on the Content of Hepatocyte Mitochondrial DNA in Aging Model Rats
Li Li,Zhao Zhien,Xu Yao,Li Lihong. Effect of Moxibustion on the Content of Hepatocyte Mitochondrial DNA in Aging Model Rats[J]. Journal of Shanxi College of Traditional Chinese Medicine, 2007, 8(5): 11-13
Authors:Li Li  Zhao Zhien  Xu Yao  Li Lihong
Affiliation:Guiyang Medical University, Guiyang Guizhou 550004
Abstract:
Objective: To observe the effect of moxibustion on the content of hepatocyte mitochondrial DNA in aging model rats. Methods: 36 rats were randomly divided into 3 groups, young control group, model group and moxibustion treatment group. The contents of hepatocyte mitochondrial DNA were measured by ultraviolet spectrophotometry. Results: Compared with the young control group, the contents of hepatocyte mitochondrial DNA were remarkably increased in aging model group; Compared with the aging model group, the contents of hepatocyte mitochondrial DNA in moxibustion treatment group were significantly decreased. Conclusions: Moxibustion can decrease the content of hepatocyte mitochondrial DNA and delay the senility.
Keywords:aging  moxibustion  the content of mitochondrial DNA
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