Kinetics of severe acute respiratory syndrome (SARS) coronavirus-specific antibodies in 271 laboratory-confirmed cases of SARS |
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Authors: | He Zhongping Dong Qingming Zhuang Hui Song Shujing Peng Guoai Luo Guangxiang Dwyer Dominic E |
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Institution: | Beijing Ditan Hospital, People's Republic of China. zhongpinghe@yahoo.com |
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Abstract: | The sensitivities and specificities of an immunofluorescence assay and an enzyme immunoassay for detection of antibodies specific for severe acute respiratory syndrome coronavirus (SARS-CoV) were compared for 148 laboratory-confirmed SARS cases. The appearance and persistence of SARS-CoV-specific antibodies were assessed, with immunoglobulin G detected in 59% of samples collected within 14 days and persisting for 60 to 95 days after the onset of illness. |
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